Praziquantel Tablets 600 mg

Praziquantel Tablets are a medication used to treat infections caused by certain types of parasitic worms, particularly schistosomiasis and liver fluke infections. Praziquantel works by paralyzing and killing the worms, which are then expelled from the body through natural processes.

Key Information:

1. Uses:

• Schistosomiasis: A disease caused by parasitic worms of the Schistosoma species.
• Liver flukes: Infections caused by parasites like Clonorchis sinensis or Fasciola hepatica.
• Sometimes used for treating infections by tapeworms (cestodes).

2. Mechanism of Action:

• Praziquantel increases the permeability of the worm’s cell membranes to calcium ions. This leads to paralysis and eventual death of the parasites.
• It also damages the parasite’s outer skin (tegument), making it more vulnerable to the host’s immune response.

3. Dosage:

• The dose and duration depend on the specific type of infection, the severity, and the patient’s body weight.
• Typically, it is administered as a single dose or over one to three days.

4. How to Take:

• Tablets are taken orally with water, usually after a meal.
• Swallow the tablet whole or split it if scored; crushing the tablet may make it bitter.

5. Side Effects:

Common side effects include:

• Nausea
• Headache
• Dizziness
• Abdominal discomfort
• Fatigue

Severe reactions are rare but may occur if there’s a heavy parasite load (due to the body’s immune reaction to dying parasites).

6. Precautions:

• Not recommended during the first trimester of pregnancy unless necessary.
• Should not be used in people with severe liver or kidney dysfunction without medical advice.
• Avoid driving or operating heavy machinery after taking the medication, as it can cause drowsiness or dizziness.

7. Availability:

• Often sold under brand names such as Biltricide, and available as generic versions in many countries.
• Usually prescribed and not available over the counter.

If you or someone needs Praziquantel, consult a healthcare provider for proper diagnosis and treatment guidance.